Lesinurad Tablet Relative Bioavailability

Exclusion Criteria

• ˗ Subject has a history or clinical manifestations of significant metabolic, hematological, pulmonary, cardiovascular, gastrointestinal, neurologic, hepatic, renal, urological, or psychiatric disorders.
• ˗ Subject has a history or suspicion of kidney stones.
• ˗ Subject has a history of asthma.
• ˗ Subject has undergone major surgery within 3 months prior to Day 1.
• ˗ Subject has donated blood or experienced significant blood loss (> 450 mL) within 12 weeks prior to Day 1 or gave a plasma donation within 4 weeks prior to the Screening visit.
• ˗ Subject has inadequate venous access or unsuitable veins for repeated venipuncture.