Exacerbations and Real-World Outcomes Among Patients with Chronic Obstructive Pulmonary Disease Following Severe Exacerbation

Inclusion Criteria

• Inclusion Criteria:
• • ≥ 1 prescription(s) fill for BGF on or following January 1, 2021
• • Patients must have evidence of a severe qualifying exacerbation event.
• o The qualifying severe exacerbation event discharge date must occur within the 180-day period preceding the initiation of BGF for classification of patients into
• prompt or delayed initiators of BGF.
• o The discharge date of the first (earliest) observed qualifying index exacerbation
• event will be set as the index date
• • ≥ 12 months of continuous health plan enrollment preceding the qualifying index
• exacerbation event date (baseline period)
• • ≥ 1 day of continuous enrollment following the qualifying index exacerbation date
• • Age ≥ 40 years on the qualifying index exacerbation date
• Exclusion Criteria:
• • Presence of cancer diagnoses other than basal or squamous cell skin cancer during the
• baseline period preceding the index date or entire follow-up period
• • Presence of ≥2 claims with a diagnosis of interstitial fibrosis or sarcoidosis diagnoses
• during the period preceding the index date or entire follow-up period
• • Presence of SITT at any time during the entire available history of patients’ data
• preceding the index date through BGF initiation