Study identifier:D1883C00002
ClinicalTrials.gov identifier:NCT01584739
EudraCT identifier:2011-005585-25
CTIS identifier:N/A
A Phase I, Single Centre, Double-Blind, Randomised, Placebo- controlled, Parallel-group Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Ascending Inhaled Doses of AZD8683 in Healthy Volunteers and COPD patients
COPD
Phase 1
Yes
AZD8683, Placebo
All
30
Interventional
18 Years +
Allocation: Randomized
Endpoint Classification: Safety Study
Intervention Model: Parallel Assignment
Masking: Double Blind
Primary Purpose: Basic Science
Verified 01 Apr 2025 by AstraZeneca
AstraZeneca
-
This study will investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of multiple ascending inhaled doses of AZD8683 in Healthy volunteers and repeated inhalation of one dose level of AZD8683 in patients with chronic obstructive pulmonary disease given once daily.
A Phase I, Single Centre, Double-Blind, Randomised, Placebo- controlled, Parallel-group Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Ascending Inhaled Doses of AZD8683 in Healthy Volunteers and COPD patients
Location
Location
LONDON, United Kingdom
Arms | Assigned Interventions |
---|---|
Experimental: AZD8683 | Drug: AZD8683 Multiple dose, oral inhalation (Healthy volunteers) Multiple dose, oral inhalation (COPD patients) |
Placebo Comparator: Placebo to AZD8683 | Drug: Placebo Multiple dose, oral inhalation (Healthy volunteers) Multiple dose, oral inhalation (COPD patients |
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