EU Clinical Trial Information System (CTIS)

Explanation of how the number of participants for analysis was determined. Includes whether analysis was per protocol, intention to treat, or another method. Also provides relevant details such as imputation technique, as appropriate.

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Official Title

The primary purpose of this study is to compare the efficacy of AZD6244 (ARRY-142886) with temozolomide in patients with advanced melanoma

Randomised study to compare the efficacy of AZD6244 vs TMZ

Cancer Study Locator (US and Canada only)

Research Site

A Phase II, Multi-centre, Open-Label, Parallel Group, Randomised Study To Compare the Efficacy of AZD6244 vs Temozolomide in Patients with Unresectable AJCC Stage 3 or 4 Malignant Melanoma

Arms	Assigned Interventions
Active Comparator: 1 Temozolomide	Drug: Temozolomide oral
Experimental: 2 AZD6244	Drug: AZD6244 Oral liquid or Capsule Other Name: ARRY-142886

Randomised study to compare the efficacy of AZD6244 vs TMZ

Official Title

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Documents available

Cancer Study Locator (US and Canada only)

CSR-1839IL-0151.pdf

Trial Results Summaries

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