study To Assess the Pharmacokinetics of AZD1656 during Coadministration with Simvastatin
Study identifier:D1020C00029
ClinicalTrials.gov identifier:N/A
EudraCT identifier:N/A
CTIS identifier:N/A
Study Complete
Official Title
A Randomized, Open-label, 3-way Crossover Phase I Study in Type 2 Diabetes Mellitus Patients Treated with Metformin to Evaluate the Pharmacokinetics and Pharmacodynamics of Simvastatin during Coadministration with AZD1656 and to Evaluate the Pharmacokinetics of AZD1656 during Coadministration with Simvastatin
Medical condition
Type 2 Diabetes Mellitus
Phase
Phase 1
Healthy volunteers
No
Study drug
AZD1656, simvastatin
Sex
All
Actual Enrollment
44
Study type
Interventional
Age
18 Years +
Date
Study Start Date: 01 Mar 2010
Primary Completion Date: 01 Aug 2010
Study Completion Date: 01 Aug 2010
Study design
Allocation: Randomized
Endpoint Classification: Pharmacokinetics/dynamics Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Other
Verification:
Verified 01 Nov 2013 by AstraZeneca Pharmaceuticals
Sponsors
AstraZeneca Pharmaceuticals
Collaborators
-
Inclusion and exclusion criteria
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No locations available
| Arms | Assigned Interventions |
|---|---|
| Experimental: 1 AZD1656 | Drug: AZD1656 Oral tablet, BID dose |
| Experimental: 2 Simvastatin | Drug: simvastatin Oral tablet, single dose |
| Experimental: 3 AZD1656 + simvastatin | Drug: AZD1656 Oral tablet, BID dose Drug: simvastatin Oral tablet, single dose |
Contacts
Investigators
Principal Investigator
Jolene K. Berg
Cetero Research, Inc.
