Study identifier:CIC-RR-001
ClinicalTrials.gov identifier:NCT02155881
EudraCT identifier:N/A
CTIS identifier:N/A
A Multi-Center, Double-Blind, Placebo-Controlled, Two-Arm, Parallel-Group, Phase III (Registration) Study to Assess the Efficacy and Safety of Ciclesonide Nasal Spray (Omnaris®) 200 mcg Once Daily in the Treatment of the Patients with Seasonal Allergic Rhinitis (SAR) in Russia
Seasonal Allergic Rhinitis
Phase 3
No
Ciclesonide, Ciclesonide Placebo
All
80
Interventional
18 Years +
Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind
Primary Purpose: Treatment
Verified 01 Dec 2016 by AstraZeneca
AstraZeneca
-
The purpose of this study is to explore the efficacy and safety of Ciclesonide Nasal Spray 200 microgram (mcg) once daily in the treatment of seasonal allergic rhinitis (SAR) in Russian participants.
The drug being tested in this study is called ciclesonide. Ciclesonide is being tested to treat allergy symptoms in people who have SAR. This study will look at improvement of allergy symptoms in Russian participants who take ciclesonide nasal spray. The study will enroll approximately 80 participants. Participants will be randomly assigned (by chance, like flipping a coin) to one of the two treatment groups—which will remain undisclosed to the participant and study doctor during the study (unless there is an urgent medical need): • Ciclesonide nasal spray 200 mcg • Placebo nasal spray (dummy inactive nasal spray) - this is a nasal spray that looks like the study drug but has no active ingredient. All participants will be asked to take 2 actuations per nostril at the same time each day throughout the study, and will be asked to record the severity of their allergy symptoms twice a day in a diary. This multi-centre trial will be conducted in Russia. The overall time to participate in this study is up to 5 weeks. Participants will make 3 visits to the clinic, and will be contacted by telephone 14 days after last dose of study drug for a follow-up assessment.
Location
Location
Moscow, Russian Federation
Location
Saratov, Russian Federation
Location
Kazan, Russian Federation
Location
Stavropol, Russian Federation
Location
Krasnodar, Russian Federation
Arms | Assigned Interventions |
---|---|
Experimental: Ciclesonide 200 mcg Ciclesonide 200 mcg nasal spray, 2 actuations (sprays) per nostril (50 mcg ciclesonide/actuation), daily, for 2 weeks. | Drug: Ciclesonide Ciclesonide nasal spray 50 mcg/actuation Other Name: Omnaris® |
Placebo Comparator: Placebo Ciclesonide placebo-matching nasal spray, 2 actuations (sprays) per nostril, daily, for 2 weeks. | Drug: Ciclesonide Placebo Ciclesonide placebo-matching nasal spray |
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