Irinotecan, 5-Fluorouracil and Leucovorin with or without Iressa in the treatment of metastatic colorectal cancer

Exclusion Criteria

• - No presence of Central Nervous System metastases
• - No other co-existing malignancies or malignancies diagnosed within the last 5 years with the exception of basal cell carcinoma or cervical cancer in situ
• - Any evidence of severe or uncontrolled systemic disease (e.g. unstable or uncompensated respiratory, cardiac, hepatic or renal disease)